Plasma ACTH and melanocyte-stimulating hormone in nail pigmentation.
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چکیده
منابع مشابه
Plasma ACTH and melanocyte-stimulating hormone in nail pigmentation.
occur with some anticancer agents such as cyclophosphamide (Shah et al., 1975), 5-FU and nitrogen mustard (Moore and Meiselbaugh, 1975), and also with exposure to x-rays (Sutton, 1952; Inalshingh, 1972). Priestman and James (1975) reported 3 cases in which nail changes were possibly due to doxorubicin. They speculated that this drug has a selective hormone-suppressive action which might allow a...
متن کاملY2-Melanocyte-Stimulating Hormone
Peptides of the pro-opiocortin class produce pronounced cardiovascular and natriuretic actions. We have investigated the acute cardiovascular effects of one of the most potent members of this class, y2-melanocyte stimulating hormone (y2-MSH), in rats. Pressor actions of y2MSH administered systemicaMy were eliminated by ganglionic blockade with chlorisondamine. Peripheral cholinergic blockade fa...
متن کاملPlasma α-melanocyte stimulating hormone predicts outcome in ischemic stroke.
BACKGROUND AND PURPOSE α-Melanocyte stimulating hormone (α-MSH) is an endogenously produced neuropeptide derived from the same precursor as adrenocorticotropic hormone. α-MSH has profound immunomodulatory properties and may also be neuroprotective. Nothing is known about α-MSH and changes in its plasma concentrations in patients with acute ischemic stroke. METHODS In this prospective observat...
متن کاملDesacetyl-α-melanocyte stimulating hormone and α-melanocyte stimulating hormone are required to regulate energy balance
OBJECTIVE Regulation of energy balance depends on pro-opiomelanocortin (POMC)-derived peptides and melanocortin-4 receptor (MC4R). Alpha-melanocyte stimulating hormone (α-MSH) is the predicted natural POMC-derived peptide that regulates energy balance. Desacetyl-α-MSH, the precursor for α-MSH, is present in brain and blood. Desacetyl-α-MSH is considered to be unimportant for regulating energy b...
متن کاملEndogenous ACTH, not only alpha-melanocyte-stimulating hormone, reduces food intake mediated by hypothalamic mechanisms.
ACTH and alpha-melanocyte-stimulating hormone (alpha-MSH) are both consecutively processed from proopiomelanocortin (POMC), which is synthesized in hypothalamic arcuate neurons innervating the paraventricular nuclei (PVN). POMC secretion/synthesis is regulated by energy availability. ACTH and alpha-MSH bind with equal affinity to melanocortin-4 receptors and elicit similar effects on signal tra...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1978
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.53.3.249